The project (acronym TEPCAN) addresses very ambitious and responsible transnational research program, development and innovation in the field of nano(bio)technology for targeted and personalized therapies of human lung cancer.
The near future of personalized nanomedicine lies in the development of multifunctional nanosystems that can not only deliver the desired therapeutics to specific molecular targets in cancer cells, but also treat and allow real-time monitoring of cellular treatment with relevant imagining modalities (theranostics). Now, in the new millennium, as next generation transporters move out beyond the classical cancer treatments, and come into the nanotechnology field, there is an urgent need and real scientific challenge to develop “smart” nanocarriers that will be enable to (i) load different cargos into the personalized transporters, (ii) successfully pass such cargos through different intracellular barriers without causing any foreign body immune responses and/or local and systemic toxicity events, (iii) release it into the lung cancer cell targets or nearby surrounded compartments, and finally (iv) allow to visualize of this entire process without degrading the cargos. With the advances of the synthetic biology and nanotechnology, we address a very ambitious scientific translation research program focusing to bioengineering of theranostic exosomes to be examined for regulatory efficacy and safety studies.
“Together Everyone Achieves More” (TEAM) is the major transnational idea placed in the project. The project merges national and international laboratories, clinics and industrial partners assembling the interdisciplinary team of scientists, medical doctors and business ventures from Poland and Norway spanning the fields of different chemical, biomedical and economical sciences. These collective skills of the international consortium allow conducting the envisioned transnational studies crossing borders and ideas in cancer nanotechnology.
The project is divided into 7 work packages of each includes the respective tasks. The project time-table and research objectives is well-balanced to reach all milestones and deliverables based on the project agenda addressing to the Gantt Chart (please see below).
